When Cancer Vaccines Go Viral.

Repáraz, David; Llopiz, Diana; Sarobe, Pablo · Clin Cancer Res · 2019

editorial · Level V

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Abstract

Induction of antitumor responses by vaccines requires strong immunogens. Heterologous viral prime/boost immunization with the BN-CV301 vaccine promotes activation of immune responses that provide a clinical benefit to patients with cancer. This viral platform may be used to harbor different antigens and prime tumor immunity potentially useful for combinatorial strategies.<i>See related article by Gatti-Mays et al., p. 4933</i>.

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