PennPET Explorer: Design and Preliminary Performance of a Whole-Body Imager.
Where this comes from
- Record sourced from PubMed, PMID 31227573.
- Also identified by DOI 10.2967/jnumed.119.229997 and PMC identifier 6954465.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We report on the development of the PennPET Explorer whole-body imager. <b>Methods:</b> The PennPET Explorer is a multiring system designed with a long axial field of view. The imager is scalable and comprises multiple 22.9-cm-long ring segments, each with 18 detector modules based on a commercial digital silicon photomultiplier. A prototype 3-segment imager has been completed and tested with an active 64-cm axial field of view. <b>Results:</b> The instrument design is described, and its physical performance measurements are presented. These include sensitivity of 55 kcps/MBq, spatial resolution of 4.0 mm, energy resolution of 12%, timing resolution of 256 ps, and a noise-equivalent count rate above 1,000 kcps beyond 30 kBq/mL. After an evaluation of lesion torso phantoms to characterize quantitative accuracy, human studies were performed on healthy volunteers. <b>Conclusion:</b> The physical performance measurements validated the system design and led to high-quality human studies.
Medical subject headings
- Positron-Emission Tomography
- Whole Body Imaging