Recognizing diversity in parietal epithelial cells.
Level V
Where this comes from
- Record sourced from PubMed, PMID 31229027.
- Also identified by DOI 10.1016/j.kint.2019.02.036.
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Abstract
Parietal epithelial cells comprise a heterogeneous cell population lining Bowman's capsule. The study by Kuppe et al. focused on the peritubular region of Bowman's capsule and explored the cell biology of 2 poorly characterized subtypes-the intermediate and the cuboidal parietal epithelial cells. The early and exuberant proliferative response of these subgroups in murine focal segmental glomerulosclerosis (FSGS) and human glomerular tip lesions identified a novel hot spot for glomerular lesion formation.
Medical subject headings
- Glomerulosclerosis, Focal Segmental
- Podocytes