Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 31230606.
- Also identified by DOI 10.1192/bjp.2019.157 and PMC identifier 7557861.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We reappraise the psychiatric potential of calcium channel blockers (CCBs). First, voltage-gated calcium channels are risk genes for several disorders. Second, use of CCBs is associated with altered psychiatric risks and outcomes. Third, research shows there is an opportunity for brain-selective CCBs, which are better suited to psychiatric indications.
Medical subject headings
- Calcium Channel Blockers
- Mental Disorders