Pattern of failure after adjuvant radiotherapy following extrapleural pneumonectomy of pleural mesothelioma in the SAKK 17/04 trial.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 31252293.
- Also identified by DOI 10.1016/j.radonc.2019.05.024.
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Abstract
Postoperative radiotherapy after extrapleural pneumonectomy of malignant pleural mesothelioma was investigated in the randomized phase II trial SAKK17/04. The relapse rate within the high and/or low-dose PTV without previous distant failure was 24%, the isolated in-field-relapse rate within the PTVs was 5% and the distant relapse rate outside of the PTVs was 81%. Clinical outcome was mainly determined by distant disease progression outside of the radiation field.
Medical subject headings
- Lung Neoplasms
- Mesothelioma
- Neoplasm Recurrence, Local
- Pleural Neoplasms