T2D Risk Genes: Exome Sequencing Goes Straight to the Source.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 31269421.
- Also identified by DOI 10.1016/j.cmet.2019.06.010.
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Abstract
Genome-wide association studies have identified hundreds of genomic variants associated with human T2D risk, but translating such findings to clinically useful information has proved challenging. A new study in Nature (Flannick et al., 2019) breaks this gridlock, using direct exome sequencing to identify functional coding variants, providing critical complementary gene-level information.
Medical subject headings
- Diabetes Mellitus, Type 2
- Genome-Wide Association Study