Design of vaccine efficacy trials during public health emergencies.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 31270270.
- Also identified by DOI 10.1126/scitranslmed.aat0360 and PMC identifier 6613811.
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Abstract
Public health emergencies, such as an Ebola disease outbreak, provide a complex and challenging environment for the evaluation of candidate vaccines. Here, we outline the need for flexible and responsive vaccine trial designs to be used in public health emergencies, and we summarize recommendations for their use in this setting.
Medical subject headings
- Clinical Trials as Topic
- Emergencies
- Public Health
- Vaccines