Pandemic Uropathogenic Fluoroquinolone-resistant Escherichia coli Have Enhanced Ability to Persist in the Gut and Cause Bacteriuria in Healthy Women.

Tchesnokova, Veronika L; Rechkina, Elena; Chan, Diana; Haile, Helen Ghirmai; Larson, Lydia; Ferrier, Kendra; Schroeder, David W; Solyanik, Thalia et al. · Clin Infect Dis · 2020

cross_sectional · Level IV

Where this comes from

Abstract

We report that fluoroquinolone-resistant Escherichia coli are found in feces of 8.8% of healthy women, with most bacteria belonging to pandemic multidrug-resistant ST131-H30R or ST1193 clonal groups. Moreover, these highly uropathogenic clonal groups demonstrate an especially prolonged gut persistence and high rate of bacteriuria without documented urinary tract infection.

Medical subject headings