Directly Reprogrammed Neurons Still Have Some Growing Up to Do.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 31271745.
- Also identified by DOI 10.1016/j.stem.2019.06.005.
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Abstract
Direct lineage conversion offers a fast and simple method to study mature neurons in vitro, but its utility for investigating neurodevelopment has remained unclear. In this issue of Cell Stem Cell, Chanda et al. (2019) use Ngn2-induced neurons to elucidate the pathogenic mechanisms of the teratogenic compound valproic acid.
Medical subject headings
- Neurons
- Valproic Acid