MRI identifies biochemical alterations of intervertebral discs in patients with low back pain and radiculopathy.
Level V
Where this comes from
- Record sourced from PubMed, PMID 31278582.
- Also identified by DOI 10.1007/s00330-019-06305-6.
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Abstract
• Molecular intervertebral disc damage was associated with LBP and radiculopathy.• Patients with radiculopathy and LBP demonstrated a depletion of gagCEST values compared with healthy controls.• GagCEST imaging may be a non-invasive tool for investigation of degeneration processes of lumbar intervertebral discs (IVDs). GagCEST imaging may be an imaging biomarker for biochemical IVD alterations.
Medical subject headings
- Intervertebral Disc
- Intervertebral Disc Degeneration
- Low Back Pain
- Magnetic Resonance Imaging
- Radiculopathy