Management of Multiple Secreting Paragangliomas in a Succinate Dehydrogenase Subunit D (SDHD) Variant Carrier.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 31279790.
- Also identified by DOI 10.1016/j.athoracsur.2019.05.037.
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Abstract
Management of functional intrathoracic sympathetic paragangliomas in succinate dehydrogenase subunit D (SDHD) mutation carriers is challenging, and there is no uniform guideline for treatment to date. The risks of potential malignant behavior and long-term cardiovascular morbidity have to be weighed against the risks of treatment complications. We report the multidisciplinary and shared decision-making approach that resulted in successful surgical removal of 3 paragangliomas in a SDHD mutation carrier.
Medical subject headings
- DNA, Neoplasm
- Head and Neck Neoplasms
- Mutation
- Neoplasms, Multiple Primary
- Succinate Dehydrogenase
- Thoracic Neoplasms