Imaging of Waldenström Macroglobulinemia: A Comprehensive Review for the Radiologist in the Era of Personalized Medicine.

Abstract

<b>OBJECTIVE.</b> We describe the range of organ systems involved and the spectrum of imaging findings seen in Waldenström macroglobulinemia (WM). <b>CONCLUSION.</b> Although imaging is not mandatory in the initial workup of a patient with WM, a multimodality imaging approach can lead toward the diagnosis of a lymphoproliferative disorder, establish the tumor burden, identify sites of involvement, and thus explain the clinical presentation, help in determining prognosis and monitoring response to therapy, and help identify treatment-induced toxicity.