Designing noninferiority tuberculosis treatment trials: Identifying practical advantages for drug regimens with acceptable effectiveness.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 31299047.
- Also identified by DOI 10.1371/journal.pmed.1002850 and PMC identifier 6625704.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
In this Collection Review for the Novel Treatments for Tuberculosis Collection, Piero Olliaro and Michael Vaillant discuss the considerations when choosing a non-inferiority margin that is meaningful from statistical, ethical, clinical, and health standpoint.
Medical subject headings
- Antitubercular Agents
- Endpoint Determination
- Equivalence Trials as Topic
- Research Design
- Tuberculosis