What Prophylactic Antibiotic (Type, Dose and Route of Administration) Should Be Administered Perioperatively for Patients Undergoing Total Ankle Arthroplasty (TAA)?
expert_opinion · Level V
Where this comes from
- Record sourced from PubMed, PMID 31322947.
- Also identified by DOI 10.1177/1071100719859009.
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Abstract
The administration of prophylactic antibiotics before total ankle arthroplasty (TAA) potentially reduces the incidence of surgical site infection (SSI) and/or periprosthetic joint infection (PJI). Weight-based (of at least 2 g) cefazolin administered intravenously within 60 minutes before the procedure can be an adequate choice for antibiotic prophylaxis. If the patient has a beta-lactam anaphylaxis, we recommend an appropriate alternative antibiotic effective against Staphylococcus. It is unclear whether prophylaxis should be given as a single dose or as multiple doses. Strong. Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus).
Medical subject headings
- Anti-Bacterial Agents
- Antibiotic Prophylaxis
- Arthroplasty, Replacement, Ankle
- Cefazolin
- Prosthesis-Related Infections
- Surgical Wound Infection
Anatomy
- ankle