DNA Methylation as a Robust Classifier of Epithelial Ovarian Cancer.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 31337645.
- Also identified by DOI 10.1158/1078-0432.CCR-19-1797.
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Abstract
Epithelial ovarian cancers (EOC) can be defined across different histologic subtypes by specific DNA methylation profiles which correlate with outcome. Identification of distinct EOC methylation subgroups emphasizes the role of epigenetic remodeling to establish unique EOC etiology during transformation, and harbors the potential to direct personalized medicine and patient care.<i>See related article by Bodelon et al., p. 5937</i>.
Medical subject headings
- Carcinoma, Ovarian Epithelial
- Neoplasms, Glandular and Epithelial
- Ovarian Neoplasms