Depletion-of-susceptibles Bias in Analyses of Intra-season Waning of Influenza Vaccine Effectiveness.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 31351439.
- Also identified by DOI 10.1093/cid/ciz706 and PMC identifier 7318775.
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Abstract
Bias arises in studies of waning vaccine effectiveness when higher-risk individuals are depleted from the at-risk population at different rates between study groups. We examined how this bias arises and how to avoid it. A reanalysis of data from California confirmed a finding of intra-season waning of influenza vaccine effectiveness.
Medical subject headings
- Influenza Vaccines
- Influenza, Human