Factors Influencing the Incubation of an Infectious Form of Creutzfeldt-Jakob Disease.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 31351441.
- Also identified by DOI 10.1093/cid/ciz692.
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Abstract
The French epidemics of iatrogenic Creutzfeldt-Jakob disease after growth hormone (GH) treatment provide an opportunity to understand factors governing the inter-human transmission of prions. The present analysis relying on truncated Weibull distribution supports a relationship between host genetics, dose of the at-risk GH, age at treatment onset, and duration of the incubation period.
Medical subject headings
- Communicable Diseases
- Creutzfeldt-Jakob Syndrome
- Prions