Clinical Utility of Highly Purified 10% Liquid Intravenous Immunoglobulin in Kawasaki Disease.

Oda, Takuya; Nagata, Hazumu; Nakashima, Yasutaka; Nanishi, Etsuro; Takada, Yui; Nishimura, Manao; Kubo, Eiji; Hatae, Ken et al. · J Pediatr · 2019

Level III

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Abstract

Compared with a 5% intravenous immunoglobulin, a 10% intravenous immunoglobulin as the first-line treatment of Kawasaki disease significantly reduced the fever duration (10 vs 13 hours, P = .022) among the responders, and the interval to adjunctive therapy for nonresponders (47 vs 49 hours, P = .035). There were no severe adverse events.

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