A Radiologist's Guide to the Changing Treatment Paradigm of Advanced Non-Small Cell Lung Cancer: The ASCO 2018 Molecular Testing Guidelines and Targeted Therapies.

Chen, Lydia; Smith, Daniel A; Somarouthu, Bhanusupriya; Gupta, Amit; Gilani, Kianoush Ansari; Ramaiya, Nikhil H · AJR Am J Roentgenol · 2019

review · Level V

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Abstract

<b>OBJECTIVE.</b> The purpose of this article is to provide an imaging-based guide of the modern genomic classifications and targeted therapies for advanced non-small cell lung cancer (NSCLC) with an emphasis on the relevance of the 2018 American Society of Clinical Oncology molecular testing guidelines for radiologists. <b>CONCLUSION.</b> Knowledge of the radiologic relevance of lung cancer driver mutations and modern targeted agents is essential for imaging interpretation of advanced NSCLC in the modern age of precision medicine.

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