Unconventional ST2- and CD127-negative lung ILC2 populations are induced by the fungal allergen Alternaria alternata.
Level V
Where this comes from
- Record sourced from PubMed, PMID 31369800.
- Also identified by DOI 10.1016/j.jaci.2019.07.018 and PMC identifier 6938690.
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Abstract
We demonstrate that unconventional ST2- and CD127-negative ILC2 populations are present in mouse lung and are induced by <i>Alternaria</i>, suggesting commonly used ILC2 identification practices do not accurately enumerate the total burden of type 2 cytokine producing ILC2s.
Medical subject headings
- Alternaria
- Alternariosis
- Hypersensitivity
- Lymphocyte Subsets
- Lymphocytes