DNA functionalization of colloidal particles via physisorption of azide-functionalized diblock copolymers.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 31372613.
- Also identified by DOI 10.1039/c9sm01243e.
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Abstract
DNA-coated inorganic particles can be prepared simply by physical adsorption of azide-functionalized diblock copolymers (polystyrene-b-poly(ethylene oxide)-azide, PS-b-PEO-N<sub>3</sub>) onto hydrophobically-modified inorganic particles, followed by strain-promoted azide-alkyne cycloaddition (SPAAC, copper-free click chemistry). This approach is applied to organosilica, silica and titania particles. The DNA-coated colloids are successfully crystallized into colloidal superstructures by a thermal annealing process using DNA-mediated assembly.
Medical subject headings
- Alkynes
- Azides
- Colloids
- DNA
- Polymers
- Silicon Dioxide
- Titanium