Cutting Off Leukemogenesis: Hydra-like Plasticity of Mature Leukemic Cells.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 31374194.
- Also identified by DOI 10.1016/j.stem.2019.07.005.
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Abstract
Leukemic stem cells (LSCs) in acute myeloid leukemia (AML) can drive tumor growth and relapse. In this issue of Cell Stem Cell, McKenzie et al. (2019) report that some mature leukemic cells can de-differentiate and contribute to AML tumorigenesis, a finding with important implications for therapies focused on eradicating LSCs.
Medical subject headings
- Hydra
- Leukemia, Myeloid, Acute