Anosognosia for hemiplegia as a tripartite disconnection syndrome.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 31383259.
- Also identified by DOI 10.7554/eLife.46075 and PMC identifier 6684265.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The syndrome of Anosognosia for Hemiplegia (AHP) can provide unique insights into the neurocognitive processes of motor awareness. Yet, prior studies have only explored predominately discreet lesions. Using advanced structural neuroimaging methods in 174 patients with a right-hemisphere stroke, we were able to identify three neural systems that contribute to AHP, when disconnected or directly damaged: the (i) premotor loop (ii) limbic system, and (iii) ventral attentional network. Our results suggest that human motor awareness is contingent on the joint contribution of these three systems.
Medical subject headings
- Agnosia
- Hemiplegia
- Psychomotor Performance
- Stroke