Rewiring regulatory T cells for tumour killing.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 31384007.
- Also identified by DOI 10.1038/s41551-019-0443-y and PMC identifier 7268916.
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Abstract
In mouse models of cancer, the inhibition of a set of regulatory proteins improves checkpoint-blockade therapy by causing regulatory T cells to produce the cytokine interferon-γ.
Medical subject headings
- Interferon-gamma
- Neoplasms
- T-Lymphocytes
- T-Lymphocytes, Regulatory