Acyl-CoA-Binding Protein Fuels Gliomagenesis.
Where this comes from
- Record sourced from PubMed, PMID 31390546.
- Also identified by DOI 10.1016/j.cmet.2019.07.007.
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Abstract
Altered lipid metabolism is common in glioblastoma, but its role in tumorigenesis is not well understood. In this issue of Cell Metabolism, Duman et al. (2019) provide new insight into this process, demonstrating that acyl-CoA-binding protein (ACBP) drives glioblastoma growth by promoting mitochondrial long fatty acyl-CoA accumulation and β-oxidation.
Medical subject headings
- Diazepam Binding Inhibitor
- Glioblastoma