Mitochondrial DNA Inheritance in Humans: Mix, Match, and Survival of the Fittest.

Suomalainen, Anu · Cell Metab · 2019

other · Level V

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Abstract

Mitochondrial DNA (mtDNA) sequence variation and maternal inheritance are valuable tools in assessing ancestry of different human populations and for clinical practice. A new study (Wei et al., 2019) reports that the fate of new mtDNA variants in the female germline is non-random as they report functional selection and matching to nuclear ancestry to shape human mtDNA variation.

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