A Light Touch on Sociability.

Domínguez-Iturza, Nuria; Bagni, Claudia · Cell · 2019

basic_science · Level V

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Abstract

Autism spectrum disorder (ASD) is prevalent, complex, and heterogeneous, and currently there is no cure. Identifying shared mechanisms across the ASD spectrum is of utmost importance for therapeutic intervention. Orefice et al. show that tackling the GABA<sub>A</sub> receptor pathway in the peripheral somatosensory system in various ASD mouse models rescues core ASD-like phenotypes.

Medical subject headings