Point-of-Care Fibrinogen Testing in Pregnancy.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 31425220.
- Also identified by DOI 10.1213/ANE.0000000000003301.
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Abstract
Agreement between estimated fibrinogen concentration via thromboelastography and traditional assays is not established in the parturient. We therefore recruited 56 parturients and performed Clauss and functional fibrinogen level (FLEV) tests. Mean difference of measurements was 36.8 mg/dL (95% CI, 21.8-51.9) with a standard deviation of 52.8 mg/dL. Calculated limits of agreement were 140.2 mg/dL (95% CI, 166.3-114.6) and -66.6 mg/dL (95% CI, -40.8 to -92.5), within the maximum allowable difference of 165 mg/dL. We therefore conclude that while most measurements fell within the limits of agreement, more work is needed to clearly define the role of this test in the obstetric population.
Medical subject headings
- Fibrinogen
- Point-of-Care Testing
- Pre-Eclampsia
- Pregnancy Trimester, Third