Preparation of monodisperse hybrid gel particles with various morphologies via flow rate and temperature control.

Kanai, Toshimitsu; Nakai, Hiroki; Yamada, Ayaka; Fukuyama, Masafumi; Weitz, David A · Soft Matter · 2019

basic_science · Level V

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Abstract

We report a facile method for preparing monodisperse hybrid smart gel particles with various morphologies by using microfluidic techniques and the swelling-shrinking phenomenon of thermosensitive poly(N-isopropylacrylamide) (PNIPAM) gel particles. We demonstrate that PNIPAM-polyacrylamide snowman-like, raspberry-like, and dumbbell-like hybrid gel particles can be prepared by controlling the flow rate and temperature.