Stem Cell Composition of Umbilical Cord Blood Following Milking Compared with Delayed Clamping of the Cord Appears Better Suited for Promoting Hematopoiesis.

Katheria, Anup C; Amino, Ramina; Konop, Jason M; Orona, Anthony J; Kim, Elizabeth; Liu, Yang; Wu, Donlaong; Snyder, Evan Y · J Pediatr · 2020

case_control · Level III

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Abstract

In comparing placental transfusion strategies, blood obtained from an umbilical cord that has been "milked" vs one in which clamping was simply delayed contains mesenchymal stromal cells in addition to solely hematopoietic stem cells, a composition more favorable for hematopoiesis, as suggested by its superior rescue of lethally irradiated bone marrow-depleted mice.

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