Membrane Lipid Remodeling Takes Center Stage in Growth Factor Receptor-Driven Cancer Development.
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Where this comes from
- Record sourced from PubMed, PMID 31484051.
- Also identified by DOI 10.1016/j.cmet.2019.08.016.
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Abstract
Enhanced growth factor signaling is a hallmark of cancer, allowing cancer cells to thrive in a challenging environment. In this issue of Cell Metabolism, Bi et al. (2019) identify LPCAT1, a key membrane lipid remodeling enzyme, as a central link between genetically driven growth factor receptor expression, signaling, and tumor growth, highlighting lipid remodeling as a therapeutic target in cancer.
Medical subject headings
- Neoplasms