Host-Pathogen Relationship Advice: Fat Protects against a Broken Heart.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 31484052.
- Also identified by DOI 10.1016/j.cmet.2019.08.007.
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Abstract
During infection, disease tolerance promotes host health without killing the pathogen. In a recent issue of Cell, Luan et al. (2019) identify GDF15 as a central regulator of disease tolerance of bacterial and viral challenges, while preventing cardiac damage, by mediating downstream cross-organ communication via the sympathetic and metabolic systems.
Medical subject headings
- Host-Pathogen Interactions
- Immune Tolerance