Molecular imaging of bacterial infections: Overcoming the barriers to clinical translation.

Ordonez, Alvaro A; Sellmyer, Mark A; Gowrishankar, Gayatri; Ruiz-Bedoya, Camilo A; Tucker, Elizabeth W; Palestro, Christopher J; Hammoud, Dima A; Jain, Sanjay K · Sci Transl Med · 2019

review · Level V

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Abstract

Clinical diagnostic tools requiring direct sample testing cannot be applied to infections deep within the body, and clinically available imaging tools lack specificity. New approaches are needed for early diagnosis and monitoring of bacterial infections and rapid detection of drug-resistant organisms. Molecular imaging allows for longitudinal, noninvasive assessments and can provide key information about infectious processes deep within the body.

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