Clinical Validation of PBRM1 Alterations as a Marker of Immune Checkpoint Inhibitor Response in Renal Cell Carcinoma.

Braun, David A; Ishii, Yuko; Walsh, Alice M; Van Allen, Eliezer M; Wu, Catherine J; Shukla, Sachet A; Choueiri, Toni K · JAMA Oncol · 2019

prospective_cohort · Level II

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Abstract

This cohort study examines whether <i>PBRM1</i> alterations are associated with response to immune checkpoint inhibitor treatment in patients with metastatic clear cell renal cell carcinoma.