The Face of Chromatin Variants.

Flaus, Andrew; Owen-Hughes, Tom · Cell · 2019

basic_science · Level V

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Abstract

A developmental program affecting human face shape is shown by Greenberg et al. (2019) to hinge on the ability to distinguish a single methyl group between two histone variant isoforms and the action of the chromatin-remodeling enzyme SRCAP. This challenges researchers to link atomic structure to a morphological defect.

Medical subject headings