Aging of the Hematopoietic Stem Cell Niche: An Unnerving Matter.

Raaijmakers, Marc H G P · Cell Stem Cell · 2019

editorial · Level V

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Abstract

The drivers of aging in the hematopoietic system remain incompletely understood. In this issue of Cell Stem Cell, Ho et al. (2019) report that functional switching of β-adrenergic nerve signaling underlies remodeling of stem cell niches, driving age-associated alterations in hematopoiesis.

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