Investigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma.

Li, Xingnan; Hastie, Annette T; Peters, Michael C; Hawkins, Gregory A; Phipatanakul, Wanda; Li, Huashi; Moore, Wendy C; Busse, William W et al. · J Allergy Clin Immunol · 2020

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Abstract

Combination of IL-6 (non-Type 2 asthma) and FeNO or blood eosinophil count (Type 2 asthma) identified asthma endotypes related to asthma severity, exacerbations, and responsiveness to corticosteroids and potential for response to anti-Type 2 and anti-IL-6 treatment.

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