TNF induces production of type 2 cytokines in human group 2 innate lymphoid cells.

Ogasawara, Noriko; Poposki, Julie A; Klingler, Aiko I; Tan, Bruce K; Hulse, Kathryn E; Stevens, Whitney W; Peters, Anju T; Grammer, Leslie C et al. · J Allergy Clin Immunol · 2020

Level V

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Abstract

TNF receptor II is expressed on ILC2s and TNF is able to induce production of type 2 cytokines in human ILC2s. TNF may play a role in causing or amplifying type 2 immunity contributing to health and disease.

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