Angiotensin-(1-7) for diabetic kidney disease: better than an angiotensin-converting enzyme inhibitor alone?
expert_opinion · Level V
Where this comes from
- Record sourced from PubMed, PMID 31543149.
- Also identified by DOI 10.1016/j.kint.2019.05.028.
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Abstract
In this commentary we emphasize the renoprotective effect of cyclic angiotensin-(1-7) described by Cassis et al. in a mouse model of diabetic kidney disease. The importance of the study is that this peptide was even more protective than the angiotensin-converting enzyme inhibitor lisinopril administered alone and that when the 2 componds were combined, the renoprotective action was additive.
Medical subject headings
- Diabetes Mellitus
- Diabetic Nephropathies