Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 31552412.
- Also identified by DOI 10.1093/cid/ciz733 and PMC identifier 7146005.
- Licence recorded as CC BY-NC-ND.
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Abstract
End-organ impairment has received relatively little research attention as a possible manifestation of tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS). In this prospective cohort study, one-half of adults with human immunodeficiency virus and pulmonary tuberculosis experienced meaningful declines in lung function on antiretroviral therapy, suggesting a role for lung function in TB-IRIS definitions.
Medical subject headings
- HIV Infections
- Immune Reconstitution Inflammatory Syndrome
- Tuberculosis