Breathe: Your Mitochondria Will Do the Rest… If They Are Healthy!
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 31577932.
- Also identified by DOI 10.1016/j.cmet.2019.09.004.
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Abstract
Dysfunctions of the mitochondrial electron transport chain cause severe, currently untreatable, diseases in humans. A new study by Jain et al. (2019) reports increased oxygen levels in the brain of complex-I-deficient mice. Reducing the O2 levels by hypoxia, carbon monoxide, or anemia, improved the clinical phenotype and prolonged the lifespan of the mouse model.
Medical subject headings
- Hyperoxia
- Leigh Disease