ctDNA in Gastric and Gastroesophageal Cancer: Prognostic, Predictive, or Preliminary?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 31582518.
- Also identified by DOI 10.1158/1078-0432.CCR-19-2774.
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Abstract
In gastric and gastroesophageal adenocarcinoma, circulating tumor DNA identifies molecular drivers missed using routine tumor biopsy, can refine patient selection for targeted therapy, and may be prognostic following surgical resection. However, lack of standardization could impede adoption of this technology as a clinically useful tool; prospective validation in clinical trials is required.<i>See related article by Maron et al., p. 7098</i>.
Medical subject headings
- Adenocarcinoma
- Circulating Tumor DNA
- Esophageal Neoplasms