Engineered Stem Cells Provide Cancer-Killing iNKT Cells.

Murray, Mallory Paynich; Kronenberg, Mitchell · Cell Stem Cell · 2019

editorial · Level V

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Abstract

Invariant natural killer T (iNKT) cells have been tested for their potential use in cancer immune therapy, but their low frequency has limited their use. In this issue, Zhu and colleagues propose to overcome this by engineering hematopoietic stem cells (HSCs) to provide a continual source of iNKT cells. (Zhu et al., 2019).

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