Platelet-rich Blood Derivatives for Tendon Regeneration.

Costa-Almeida, Raquel; Babo, Pedro S; Reis, Rui L; Gomes, Manuela E · J Am Acad Orthop Surg · 2020

review · Level V

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Abstract

Tendon injuries constitute a significant healthcare problem with variable clinical outcomes. The complex interplay of tissue homeostasis, degeneration, repair, and regeneration makes the development of successful delivery therapeutic strategies challenging. Platelet-rich hemoderivatives, a source of supra-physiologic concentrations of human therapeutic factors, are a promising application to treat tendon injuries from the perspective of tendon tissue engineering, although the outcomes remain controversial.

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