Mechano-chromic protein-polymer hybrid hydrogel to visualize mechanical strain.

Taki, Masumi; Yamashita, Tadahiro; Yatabe, Kazuki; Vogel, Viola · Soft Matter · 2019

basic_science · Level V

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Abstract

In a proof-of-concept study, a mechano-chromic hydrogel was synthesized here, via chemoenzymatic click conjugation of fluorophore-labeled fibronectin into a synthetic hydrogel co-polymers (i.e., poly-N-isopropylacrylamide/polyethylene glycol). The optical FRET response could be tuned by macroscopic stretch.

Medical subject headings