Gasdermin D and pyroptosis in acute kidney injury.
Where this comes from
- Record sourced from PubMed, PMID 31648694.
- Also identified by DOI 10.1016/j.kint.2019.07.002.
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Abstract
Cell death is a pathophysiological component of acute tubular necrosis and acute kidney injury. Regulated necrosis, however, comes in several different forms. Although necroptosis and ferroptosis have been recently characterized in acute kidney injury, pyroptosis has not been assessed in detail. In this issue of Kidney International, Miao and Yin et al. investigate the role of gasdermin D, a protein that can form plasma membrane pores.
Medical subject headings
- Acute Kidney Injury
- Pyroptosis