IgG Fc glycosylation as an axis of humoral immunity in childhood.

Cheng, Hao D; Tirosh, Irit; de Haan, Noortje; Stöckmann, Henning; Adamczyk, Barbara; McManus, Ciara A; O'Flaherty, Róisín; Greville, Gordon et al. · J Allergy Clin Immunol · 2020

Level V

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Abstract

IgG Fc glycans were characterized in 225 healthy children and 40 children with unexplained recurrent respiratory infections, revealing age-dependent variation and suggesting a role for IgG glycosylation in immunocompetence.

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