Bioactivity of nitric acid and calcium chloride treated carbon-fibers reinforced polyetheretherketone for dental implant.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 31669982.
- Also identified by DOI 10.1016/j.jmbbm.2019.103497.
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Abstract
Carbon fiber reinforced Polyetheretherketone (PEEK) acquires mechanical strength which is close to human bone, but PEEK is inert, which can affect the bone fixation and osseointegration during dental implantation. To improve the bioactivity of PEEK, surface modification with nitric acid (HNO<sub>3</sub>) and calcium chloride (CaCl<sub>2</sub>) were utilized in this work. As the results, the hydrophilicity of the treated samples is significantly improved with the reduced roughness and attached nitro-functional group on its surface. The biological activity of CF/PEEK samples are enhanced by apatite formation evaluation soaking in simulated body fluid (SBF) in vitro after HNO<sub>3</sub> and CaCl<sub>2</sub> treatment. Moreover, the cytotoxicity experiments results confirm that surface treatment with HNO<sub>3</sub> and CaCl<sub>2</sub> is not harmful to the compatibility and safety of the cells.
Medical subject headings
- Dental Implants
- Nitric Acid