Fifty years of research on antithrombotic therapy: Achievements and disappointments.

Eur J Intern Med · 2019

review · Level V

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Abstract

The achievements with antithrombotic therapy over the past 50 years have been monumental and the disappointments relatively few. In this review, we will discuss, chronologically, the major developments of the two recognized classes of antithrombotics - anticoagulants and antiplatelet agents.