Association between Serum Ferritin and Cognitive Function in Early Childhood.

Parkin, Patricia C; Koroshegyi, Christine; Mamak, Eva; Borkhoff, Cornelia M; Birken, Catherine S; Maguire, Jonathon L; Thorpe, Kevin E; TARGet Kids! Collaboration · J Pediatr · 2020

cross_sectional · Level IV

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Abstract

In infants 1-3 years of age, we found higher serum ferritin values associated with higher cognitive function, as measured by the Mullen Scales of Early Learning (P = .02 for the nonlinear relationship). A serum ferritin of 17 μg/L corresponded to the maximum level of cognition, beyond which there was no meaningful improvement. TRIAL REGISTRATION: Clinicaltrials.gov NCT01481766 and NCT01869530.

Medical subject headings